Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer.
The polycomb group protein enhancer of zeste homologue 2 ( EZH2 ), which has histone methyltransferase (HMT) activity
The polycomb group protein enhancer of zeste homologue 2 ( EZH2 ), which has histone methyltransferase (HMT) activity
Background The molecular mechanisms that control the aggressiveness of gastric cancer (GC) remain poorly defined. Here we show that synbindin contributes to the aggressiveness
Objective Loss of surface maturation and cytonuclear atypia have been regarded as the pathological ‘gold standard’ for the diagnosis of oesophageal squamous cell intraepithelial neoplasia. However, there has been no satisfactory endomicroscopic method similar to this pathological approach to detect surface maturation and screen for oesophageal squamous cell intraepithelial neoplasia. The aim of this study was to apply a 3-dimensional (3D) confocal endomicroscopic imaging technique to investigate the surface maturation
Background and study aims: In vivo molecular imaging represents a powerful tool for the im- mediate diagnosis of gastric cancer. In this study, the monoclonal antibody MG7,
An 8-year-old boy was admitted to our hospital due to intermittent episodes of dysphagia over the past 5 years, which was severely affecting his physical growth and quality of life. He was diagnosed as having achalasia 3 years ago, and had twice undergone endoscopic balloon dila- tion
Fas signaling was reported to participate in cell apoptosis. However, this pathway has also been shown to promote tumor cell motility, leading
Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is involved in Xenopus embryonic development. Human DACT2
Human dachshund homolog 1 (DACH1) is a major component of the Retinal Determination Gene Network (RDGN) and functions as a tumor suppressor. However, the regulation of DACH1 expression and its function in hepatocellular carcinoma (HCC) remain unclear. In this study, epigenetic changes
The present study aims to determine the effect of AMPK on etoposide-induced apoptosis of cancer cells. Our results revealed that etoposide